: You can move your extracted folder to Hdd1/Content/0000000000000000/ using a USB stick or by connecting via FTP through your PC.
Instead of an Xbox 360 ISO, you might consider emulating the or Wii version of RE4 via Dolphin on PC. It’s legal if you rip your own disc, and the emulation quality often surpasses the Xbox 360 port (which had minor audio compression issues). iso resident evil 4 xbox 360 install